UC Sampdoria fell short of repeating its successful 1984–85 season, ending up in 12th position in the league. It did almost defend its cup title successfully, but despite a 2–1 victory in the first leg, it lost to Roma in the return leg. Sampdoria's European adventure did not live up to expectations, it not even reaching the quarter-finals of the Cup Winners' Cup.
Squad
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Source: RSSSF.com Rules for classification: 1) Points; 2) Head-to-head points; 3) Head-to-head goal difference; 4) Goal difference; 5) Goals scored; 6) Draw. (Note: Head-to-head record is used only after all the matches between the teams in question have been played).[1] (R) Relegated
Note: The match was awarded by the sports judge 0–2 in favor of Sampdoria, due to an object thrown from the stands, after having whistled a penalty in favor of Sampdoria, which hit the referee Redini, who was forced to suspend the match in the 7th minute of the first half of extra time with the score at 2–1 for Como.[3]