During pre-race ceremonies, the Luke Air Force Base presented the nation's colors. Pastor Rick Derbyshire would give out the invocation.16-year old Chevel Shepherd, who had won Season 15 of The Voice, would sing the national anthem. The son of the CEO of TicketGuardian. Hudson Derbyshire, accompanied by his father and CEO, Brian and his mom, gave out the starting command.
At the race start, NASCAR judged that Chase Elliott jumped the restart against Ryan Blaney, and Elliott, while leading the first couple of laps, had to make a pass through penalty on pit road. Ryan Blaney would lead the first 35 laps before being passed by Kyle Busch on lap 36. Three laps later, Erik Jones would suffer a flat tire and spin in Turn 2, causing the first caution of the day. After cycling through pit stops, Denny Hamlin would lead the field to green on lap 46, before being passed for the lead by Busch just a lap later. Busch would lead until lap 65, when Brad Keselowski also suffering a flat tire and hitting the Turn 2 wall, almost collecting Ryan Preece. After more pit stops, Ryan Blaney would restart in the lead on lap 71 and would hang on to win the first stage.
The field restarted on lap 84, with Kyle Busch leading the field to green. Busch, starting from lap 80 would go on to lead the next 73 laps. Alex Bowman would suffer a flat tire with just three laps to go in the stage, hitting the turn 1 wall. Kyle Busch would win the stage under caution.
Kyle Busch would jump to the lead on the initial restart, but a lap later Michael McDowell after missing the exit of the turn 2 wall, got hit in the rear by David Ragan and hit the wall. His car would not steer and would then hit the turn 3 wall, causing McDowell to retire. Kyle Busch would once again lead the field to the restart on lap 166, and would stay in the lead until lap 195, when Alex Bowman had another flat tire and pounded the turn 3 wall. Alex Bowman would retire from the race. Busch restarted and held on to the lead until lap 219, when Elliott spun off of turn 4. Hemric would take the lead after pit stops cycled, and restarted in first. However, on the first lap of the restart, Preece would hit the wall and clip the right front end of Daniel Suarez's car, sending Preece into the inside backstretch wall. Blaney would take the lead again, however Preece would again cause another caution, causing him to retire. Almirola would restart and take the lead until lap 251 when Blaney took the lead. Blaney held on to the lead until Busch, after a few laps battling took the lead on lap 296. Busch would pull away from Blaney and win.