Species of virus
Acanthocystis turfacea chlorella virus 1 (ATCV-1 ), also called Chlorovirus ATCV-1 or Chlorella virus ATCV-1 is a species of giant double-stranded DNA virus in the genus Chlorovirus
The host of ATCV-1 is Chlorella heliozoae Chlorella variabilis [ 1] [ 2]
Human infection
DNA from ATCV-1 has been isolated from the mucous membranes of the noses of humans. In both humans and mice, the presence of ATCV-1 on the oropharyngeal mucosa was associated with lower scores in tests of cognitive and motor skills.[ 3] [ 4] [ 5] [ 6]
References
^ Irina Agarkova; Brigitte Hertel; Xinzheng Zhang; Les Lane; Alexander Tchourbanov; David D. Dunigan; Gerhard Thiel; Michael G. Rossmann; James L. Van Etten (2014). "Dynamic attachment of Chlorovirus PBCV-1 to Chlorella variabilis" . Virology . 466– 467: 95– 102. doi :10.1016/j.virol.2014.07.002 . PMC 4254200 PMID 25240455 . ^ "SAG 211-6 Chlorella variabilis" . EPSAG The Culture Collection of Algae at the University of Göttingen, Germany . Archived from the original on 2017-09-23. Retrieved 2017-09-23 .^ Yolken, R. H.; Jones-Brando, L.; Dunigan, D. D.; Kannan, G.; Dickerson, F.; Severance, E.; Sabunciyan, S.; Talbot, C. C.; Prandovszky, E.; Gurnon, J. R.; Agarkova, I. V.; Leister, F.; Gressitt, K. L.; Chen, O.; Deuber, B.; Ma, F.; Pletnikov, M. V.; Van Etten, J. L. (2014). "Chlorovirus ATCV-1 is part of the human oropharyngeal virome and is associated with changes in cognitive functions in humans and mice" . Proc Natl Acad Sci U S A . 111 (45): 16106– 11. Bibcode :2014PNAS..11116106Y . doi :10.1073/pnas.1418895111 PMC 4234575 PMID 25349393 . ^ Yolken; et al. (2015). "Reply to Kjartansdóttir et al.: Chlorovirus ATCV-1 findings not explained by contamination" . Proceedings of the National Academy of Sciences . 112 (9): E927. Bibcode :2015PNAS..112E.927Y . doi :10.1073/pnas.1424665112 PMC 4352770 PMID 25654982 . ^ Elizabeth Pennisi (27 October 2014), "Algal virus found in humans, slows brain activity" , Science ^ Marilyn S. Petro; Irina V. Agarkova; Thomas M.Petro (May 2016). "Effect of Chlorovirus ATCV-1 infection on behavior of C57Bl/6 mice" . Journal of Neuroimmunology . 297 : 46– 55. doi :10.1016/j.jneuroim.2016.05.009 . PMID 27397075 . S2CID 38573451 .
External links
Acanthocystis turfacea chlorella virus 1
