Autologous cultured chondrocytes on porcine collagen membrane

Autologous cultured chondrocytes on porcine collagen membrane (Maci) is a treatment to correct cartilage defects in the knee.^[1] It is used to treat symptomatic, full-thickness cartilage defects of the knee with or without bone involvement.^[2][1] Autologous cultured chondrocytes on porcine collagen membrane is an autologous cellularized scaffold product.^[1] This treatment is approved by the US Food and Drug Administration (FDA).^[1] It is only administered to adults.^[1] Healthy cartilage is removed from the person's own knees and a 'scaffold' is created on which the healthy tissue growths.^[1] This is an autologous matrix-induced chondrogenesis procedure which prevents tissue rejection complications since the transplanted cartilage comes from the same person.^[3]

Autologous cultured chondrocytes on porcine collagen membrane was approved for use in the United States in May 2019.^[2]

• Microfracturing
• Knee osteoarthritis
• Knee pain

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