Examples of in vivo transdifferentiation by lineage-instructive approach List of examples of in vivo transdifferentiation through transfection
A list of examples of in vivo transdifferentiation through transfection:[ 1]
mouse hepatocytes → B cells (Pdx1)[ 2]
exocrine cells → B cells (Pdx1, Ngn3, and v-maf musculoaponeurotic fibrosarcoma oncogene family protein A)[ 3]
nonsensory cells → inner hair cells (Atoh1 and MathI)[ 4]
non cardiogenic mesoderm → cardiomyocytes (Gata4, Tbx5 and Smarcd3 or Baf60c)[ 5] Through excision:
B-cell precursors → hematopoietic progenitors(-Pax5)[ 6]
In adult ovarian follicles, granulosa and thecal cells → functional Sertoli-like and Leydig-like cells (-Foxl1)[ 7]
See also
References
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