Small nucleolar RNA SNORA35

Small nucleolar RNA SNORA35
Predicted secondary structure and sequence conservation of SNORA35
Identifiers
Symbol	SNORA35
Alt. Symbols	snoHBI-36
Rfam	RF00566
Other data
RNA type	Gene; snRNA; snoRNA; HACA-box
Domain(s)	Eukaryota
GO	GO:0006396 GO:0005730
SO	SO:0000594
PDB structures	PDBe

In molecular biology, Homo sapiens snoRA35 (also known as HBI-36) is an H/ACA box snoRNA, first cloned from a mouse adult brain cDNA library by Cavaillé et al. (2000),^[1] and is found to be specifically expressed in the choroid plexus. Its human orthologue, HBI-36 was discovered by a homology search and was discovered to be specifically expressed in the brain. Its gene resides in the second intron of the serotonin receptor 2c (5HT-2c) gene, which is predominantly expressed in choroid plexus epithelial cells. The human 5HT-2c mRNA was predicted to be 2'-O-methylated by the C/D box snoRNP HBII-52 at a position also subjected to A-to-I editing. HBI-36 has no documented RNA target.

• Page for Small nucleolar RNA SNORA35 at Rfam
• Entry for HBI-36 at snoRNABase

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