Bupivakain | |
Prodajno ime | Anekain, Bupivan, Carbostesin, Marcaina |
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Drugs.com | Monografija |
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Način primene | Intraspinalno |
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Poluvreme eliminacije | 2,7 h |
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Izlučivanje | Renalno |
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CAS broj | 2180-92-9 Y |
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ATC kod | N01BB01 (WHO), N01BB10 |
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PubChem | CID 2474 |
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IUPHAR/BPS | 2397 |
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DrugBank | DB00297 Y |
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ChemSpider | 2380 Y |
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KEGG | C07529 Y |
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ChEBI | CHEBI:3215 Y |
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ChEMBL | CHEMBL1098 Y |
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Formula | C18H28N2O |
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Molarna masa | 288,428 |
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CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C
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InChI=1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21) YKey:LEBVLXFERQHONN-UHFFFAOYSA-N Y
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Tačka topljenja | 107—108 °C (225—226 °F) |
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Bupivakain je organsko jedinjenje, koje sadrži 18 atoma ugljenika i ima molekulsku masu od 288,428 Da.[1][2][3][4]
Osobine
Reference
- ^ Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB: Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. Anesthesiology. . 105 (1). јул 2006: 217—8. PMID 16810015.
- ^ Picard J, Meek T: Lipid emulsion to treat overdose of local anaesthetic: the gift of the glob. Anaesthesia. . 61 (2). фебруар 2006: 107—9. PMID 16430560.
- ^ Knox, C.; Law, V.; Jewison, T.; Liu, P.; Ly, S.; Frolkis, A.; Pon, A.; Banco, K.; Mak, C.; Neveu, V.; Djoumbou, Y.; Eisner, R.; Guo, A. C.; Wishart, D. S. (2011). „DrugBank 3.0: A comprehensive resource for 'Omics' research on drugs”. Nucleic Acids Research. 39 (Database issue): D1035—D1041. PMC 3013709
. PMID 21059682. doi:10.1093/nar/gkq1126.
- ^ Wishart, David S.; Knox, Craig; Guo, An Chi; Cheng, Dean; Shrivastava, Savita; Tzur, Dan; Gautam, Bijaya; Hassanali, Murtaza (2008). „DrugBank: A knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Research. 36 (Database issue): D901—D906. PMC 2238889
. PMID 18048412. doi:10.1093/nar/gkm958.
- ^ Ghose, Arup K.; Viswanadhan, Vellarkad N.; Wendoloski, John J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of ALOGP and CLOGP Methods”. The Journal of Physical Chemistry A. 102 (21): 3762—3772. Bibcode:1998JPCA..102.3762G. doi:10.1021/jp980230o.
- ^ Tetko, Igor V.; Tanchuk, Vsevolod Yu.; Kasheva, Tamara N.; Villa, Alessandro E. P. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Journal of Chemical Information and Computer Sciences. 41 (6): 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
- ^ Ertl, Peter; Rohde, Bernhard; Selzer, Paul (2000). „Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties”. Journal of Medicinal Chemistry. 43 (20): 3714—3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura
Spoljašnje veze
 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
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