铁传递蛋白受体1

转铁蛋白受体1
已知的結構
PDB直系同源搜索: PDBe RCSB
識別號
别名TFRC;, CD71, T9, TFR, TFR1, TR, TRFR, p90, IMD46, transferrin receptor
外部IDOMIM190010 MGI98822 HomoloGene2429 GeneCardsTFRC
基因位置(人类
3號染色體
染色体3號染色體[1]
3號染色體
转铁蛋白受体1的基因位置
转铁蛋白受体1的基因位置
基因座3q29起始196,027,183 bp[1]
终止196,082,096 bp[1]
RNA表达模式


查阅更多表达数据
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_001313965
​NM_001313966
​NM_001128148
​NM_003234

NM_011638
​NM_001357298

蛋白序列

NP_001121620
​NP_001300894
​NP_001300895
​NP_003225

NP_035768
​NP_001344227

基因位置​(UCSC)Chr 3: 196.03 – 196.08 MbChr 16: 32.43 – 32.45 Mb
PubMed​查找[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

铁传递蛋白受体1(英語:Transferrin receptor protein 1 (TfR1)),又叫分化群CD71,在人类是由TFRC基因编码的蛋白质[5][6]铁从运铁蛋白通过胞吞作用转运到细胞需要TfR1。[7][8]

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000072274 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000022797 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Sutherland R, Delia D, Schneider C, Newman R, Kemshead J, Greaves M. Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. Proceedings of the National Academy of Sciences of the United States of America. July 1981, 78 (7): 4515–9. Bibcode:1981PNAS...78.4515S. PMC 319822可免费查阅. PMID 6270680. doi:10.1073/pnas.78.7.4515可免费查阅. 
  6. ^ Rabin M, McClelland A, Kühn L, Ruddle FH. Regional localization of the human transferrin receptor gene to 3q26.2----qter. American Journal of Human Genetics. November 1985, 37 (6): 1112–6. PMC 1684729可免费查阅. PMID 3002171. 
  7. ^ Aisen P. Transferrin receptor 1. The International Journal of Biochemistry & Cell Biology. November 2004, 36 (11): 2137–43. PMID 15313461. doi:10.1016/j.biocel.2004.02.007. 
  8. ^ Moos T. Brain iron homeostasis. Danish Medical Bulletin. November 2002, 49 (4): 279–301. PMID 12553165. 

外部链接

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