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2B类致癌物(英語:Group 2B carcinogens),為国际癌症研究机构对致癌物质的分类,此类物质(或其混合物)可能对人类致癌。截至2024年5月2日,共用323种[1]2B类致癌物(如黃樟素、四氯化碳、電磁波、抗甲狀腺藥物丙硫氧嘧啶、二異氰酸甲苯、抗愛滋病藥物齐多夫定、汽油引擎廢氣、乾洗業等),對人類為有可能致癌物,對動物為很可能也是致癌物。[2]更多詳細信息,可以搜尋國際癌症研究機構(IARC)專著。[3]
物质和物质组合
中文名稱
|
學名
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CAS号
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欧盟委员会编号 EINECS
|
備考
|
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A-a-C (2-Amino-9H-pyrido[2,3-b]indole)
|
26148-68-5
|
|
US Biological 化學試藥類
|
乙醛
|
Acetaldehyde
|
75-07-0
|
2 0
|
|
乙酰胺
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Acetamide
|
60-35-5
|
2 0
|
|
|
Acétate de médroxyprogestérone
|
71-58-9
|
2 0
|
|
|
Acétate de méthylazoxyméthanol
|
592-62-1
|
2 0
|
|
乙酸乙烯酯
|
Acétate de vinyle
|
108-05-4
|
2 0
|
|
咖啡酸
|
Acide caféique
|
331-39-5
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2 0
|
|
|
Acide chlorendique
|
115-28-6
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2 0
|
|
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二氯乙酸
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79-43-6
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2 0
|
|
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氨三乙酸
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139-13-9
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2 0
|
|
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Acrylate d'éthyle
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140-88-5
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2 0
|
|
丙烯腈
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Acrylonitrile
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107-13-1
|
2 0
|
|
阿达帕林
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Adapalene
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106685-40-9
|
|
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AF-2
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Furylfuramide 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide
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3688-53-7
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硝基蚨喃類殺菌劑,結構類似对羟基苯甲酸酯
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黃麴毒素 M1
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Aflatoxin,M1
|
6795-23-9
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2 2
|
|
對-氨基偶氮苯
|
Aniline Yellow para-Aminoazobenzene
|
60-09-3
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2 0
|
苯胺黃
|
鄰-氨基偶氮甲苯
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ortho-Aminoazotoluene
|
97-56-3
|
2 0
|
蘇丹紅IV代謝生成的物質
|
|
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
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712-68-5
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2 1
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|
胺苯吖啶
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Amsacrine
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51264-14-3
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2 5
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抗腫瘤藥,別名安丫啶、安吖啶
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鄰氨基苯甲醚
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ortho-Anisidine
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90-04-0
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2 0
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|
三氧化二锑
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Antimony trioxide
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1309-64-4
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2 1
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異黃樟
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Aramite
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140-57-8
|
|
別名殺螨特;異黃樟;殺螨劑
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金胺O
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Auramine
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492-80-8
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2 0
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工業級(technical-grade)
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重氮乙酰絲氨酸
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Azaserine
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115-02-6
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2 0
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別名氮絲氨酸;氮雜絲氨酸;重氮絲氨酸 - 用以抑制某些腫瘤生長的抗生素
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氮丙环
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Aziridine
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151-56-4
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2 0
|
|
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Benz[j]aceanthrylene
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202-33-5
|
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(多環芳香烴,PAHs)
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Benz(''a'')anthracene
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56-55-3
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2 0
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(多環芳香烴,PAHs)
|
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Benzo(b)fluoranthene
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205-99-2
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2 0
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(多環芳香烴,PAHs)
|
|
Benzo(j)fluoranthene
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205-82-3
|
2 0
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(多環芳香烴,PAHs)
|
|
Benzo(k)fluoranthene
|
207-08-9
|
2 0
|
(多環芳香烴,PAHs)
|
|
Benzo(''c'')phenanthrene
|
195-19-7
|
2 0
|
(多環芳香烴,PAHs)
|
苯并呋喃
|
Benzofurane、Benzofuran
|
271-89-6
|
2 0
|
(多環芳香烴,PAHs)
|
Benzyl violet 4B 酸性紫4B
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紫色1號,C39H40N3NaO6S2,3-[[Ethyl[4-[[4-(dimethyliminio)-2,5-cyclohexadiene-1-ylidene][4-[ethyl[3-(sodiooxysulfonyl)benzyl]amino]phenyl]methyl]phenyl]amino]methyl]benzenesulfonate
|
1694-09-3
|
2 1
|
主要用于羊毛、丝绸、锦纶的染色[4]
|
二溴新戊醇 2,2-雙(溴甲基)-1,3-丙二醇
|
2,2-Bis(bromomethyl)propane-1,3-diol
|
3296-90-0
|
2 2
|
中間體或阻燃劑[5][6]
|
博来霉素
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Bleomycin
|
11056-06-7
|
|
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Bracken fern
|
|
|
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蕨类植物;[7][8][9]
|
溴二氯甲烷
|
Bromodichloromethane
|
75-27-4
|
2 0
|
|
丁基羟基茴香醚
|
Butylated hydroxyanisole
|
25013-16-5
|
2 4
|
|
β-丁內酯
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b-Butyrolactone,别名4-甲基-β-丙酰内酯;B-丁内酯;Β-丁内酮,分子式为C4H6O2
|
3068-88-0
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2 2
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酯類,可作單體[10][11]
|
碳煙
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Carbon black
|
|
|
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四氯化碳
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Carbon tetrachloride
|
|
|
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邻苯二酚
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Catechol
|
|
|
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氯丹
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Chlordane
|
|
|
|
十氯酮
|
|
|
|
(開蓬,殺蟲﹑殺真菌藥,原商標名)
|
氯菌酸
|
六氯內-甲烯基-四氫苯二甲酸
|
|
|
毒性「氣喘、肺水腫、過敏性皮膚炎、灼熱疼痛感,視線模糊並流淚」
|
4-氯苯胺
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para-Chloroaniline
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106-47-8
|
2 0
|
|
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
|
氯仿
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1-Chloro-2-methylpropene
|
Chlorophenoxy herbicides
|
4-Chloro-ortho-phenylenediamine
|
氯丁二烯
|
百菌清
|
䓛
|
CI Acid Red 114
|
副玫瑰苯胺
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CI Direct Blue 15
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Citrus Red 2
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钴以及钴化合物 1
|
Cobalt sulfate and other soluble cobalt(II) salts
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Cocamide DEA condensate
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para-Cresidine
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苏铁素
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达卡巴嗪
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丹蒽醌 (Chrysazin, 1,8-Dihydroxyanthraquinone)
|
道諾黴素
|
滴滴涕 (p,p'-DDT)
|
N,N'-Diacetylbenzidine
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2,4-Diaminoanisole
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4,4'-二氨基二苯醚
|
2,4-Diaminotoluene
|
Dibenz[a,h]acridine
|
Dibenz[a,j]acridine
|
7H-Dibenzo[c,g]carbazole
|
Dibenzo[a,e]pyrene
|
Dibenzo[a,h]pyrene
|
Dibenzo[a,i]pyrene
|
1,2-二溴-3-氯丙烷
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2,3-Dibromopropan-1-ol
|
二氯乙酸
|
对二氯苯
|
3,3'-Dichlorobenzidine
|
3,3'-Dichloro-4,4'-diaminodiphenyl ether
|
1,2-二氯乙烷
|
二氯甲烷 (methylene chloride)
|
1,3-Dichloropropene (technical grade)
|
敌敌畏
|
1,2-Diethylhydrazine
|
Diglycidyl resorcinol ether
|
Dihydrosafrole
|
- Diisopropyl sulfate
- 3,3'-Dimethoxybenzidine (o-Dianisidine)
- 甲基黄
- trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)-vinyl]-1,3,4-oxadiazole
- 2,6-Xylidine (2,6-Dimethylaniline)
- 3,3'-Dimethylbenzidine (o-Tolidine)
- 偏二甲肼
- 3,7-Dinitrofluoranthene
- 3,9-Dinitrofluoranthene
- 1,6-Dinitropyrene
- 1,8-Dinitropyrene
- 2,4-二硝基甲苯
- 二硝基甲苯
- 1,4-二噁烷
- Disperse Blue 1
- 1,2-环氧丁烷
- 丙烯酸乙酯
- 乙苯
- 1,2-二氯乙烷
- 甲磺酸乙酯
- Foreign bodies, implanted in tissues
- Polymeric, prepared as thin smooth films (with the exception of poly(glycolic acid))
- Metallic, prepared as thin smooth films
- Metallic cobalt, metallic nickel and an alloy powder containing 66-67% nickel, 13-16% chromium and 7% iron
- 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
- Fumonisin B1
- 呋喃
- Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole)
- Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
- Glycidaldehyde
- 灰黃黴素
- HC Blue No. 1
- 七氯
- 六氯苯
- 六氯乙烷
- 六氯环己烷s
- 六甲基磷酰胺 (HMPA)
- 人類免疫缺陷病毒 type 2 (infection with)
- 人類乳突病毒es: some types other than 16, 18, 31 and 33
- 聯氨
- 1-Hydroxyanthraquinone
- Indeno[1,2,3-cd]pyrene
- Iron-dextran complex
- 異戊二烯
- 紫花果芸香碱
- 铅
- 磁場s (極低頻)
- MeA-a-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
- Medroxyprogesterone acetate
- MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
- MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
- Merphalan
- 丙烯亚胺 (Propyleneimine)
- Methylazoxymethanol acetate
- 5-Methylchrysene
- 4,4'-Methylene bis(2-methylaniline)
- 4,4'-Methylenedianiline
- Methylmercury compounds 1
- 2-Methyl-1-nitroanthraquinone (uncertain purity)
- N-Methyl-N-nitrosourethane
- Methylthiouracil
- 甲硝唑
- Michler's base (4,4'-methylene-bis(N,N-dimethyl)benzenamine)
- 米氏酮 (4,4'-bis(dimethylamino)benzophenone)
- Microcystin-LR
- 滅蟻樂
- 丝裂霉素C
- 米托蒽醌
- 野百合碱
- 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
- 萘酚平
- 萘
- 镍, metallic and alloys
- Niridazole
- 氨三乙酸 and its salts 1
- 5-Nitroacenaphthene
- 2-Nitroanisole
- 硝基苯
- 6-Nitrochrysene
- 護谷 (technical-grade)
- 2-Nitrofluorene
- 1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
- N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
- Nitrogen mustard N-oxide
- 硝基甲烷
- 2-硝基丙烷
- 1-硝基芘
- 4-Nitropyrene
- N-Nitrosodi-n-butylamine
- N-Nitrosodiethanolamine
- N-Nitrosodi-n-propylamine
- 3-(N-Nitrosomethylamino)propionitrile
- N-Nitrosomethylethylamine
- N-Nitrosomethylvinylamine
- N-Nitrosomorpholine
- N-亚硝基哌啶
- N-Nitrosopyrrolidine
- N-Nitrososarcosine
- Ochratoxin A
- Oestrogen-progestogen therapy, postmenopausal
- Oil Orange SS
- 奥沙西泮
- 坡缕石 (attapulgite) (long fibres, >5微米)
- Panfuran S (containing dihydroxymethylfuratrizine)
- 非那吡啶
- 苯巴比妥
- 酚酞
- Phenoxybenzamine hydrochloride
- Phenyl glycidyl ether
- 苯妥英
- PhIP (2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine)
- Polychlorophenols and their sodium salts (mixed exposures)
- Ponceau MX
- Ponceau 3R
- 溴酸钾
- Progestins
- Progestogen-only contraceptives
- 1,3-丙磺酸内酯
- Β-丙內酯
- 环氧丙烷
- 丙硫氧嘧啶(Propylthiouracil、PTU),抗甲狀腺藥物[12]
- 无线电波, such as, but not limited to, those associated with 移动电话 [13]
- 耐火陶瓷纤维
- 瑞德灵
- 黃樟素Safrole
- 日本血吸虫 (infection with)
- Sodium orthophenyl phenol
- Special-purpose fibres such as E-glass and '475' glass fibres
- Sterigmatocystin
- 链脲佐菌素
- 苯乙烯
- Sulfallate
- 四氟乙烯
- 四硝基甲烷
- 硫乙醯胺
- 4,4'-Thiodianiline
- Thiouracil
- 二氧化鈦
- 二異氰酸甲苯(2,4-Toluene diiso-cyanate, 2,4-TDI)[14][15][16]
- 三氯氮芥 (Trimustine hydrochloride)
- Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
- Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
- 台盼蓝
- 乌拉莫司汀
- 五氧化二钒
- 乙酸乙烯酯
- 4-乙烯基环己烯
- 4-Vinylcyclohexene diepoxide
- 扎西他滨
- 齐多夫定(Zidovudine,AZT)
- 阿斯巴甜[17]
混合物
接触场合
注释
- 脚注
- ^1 Evaluated as a group.
- ^2 There is limited evidence in humans that coffee drinking is carcinogenic in the urinary bladder.
- ^3 There is some evidence of an inverse relationship between coffee drinking and cancer of the large bowel.
引用
- ^ Agents Classified by the IARC Monographs, Volumes 1–135. [2024-05-10]. (原始内容存档于2024-05-02).
- ^ 談環境中的致癌物 (页面存档备份,存于互联网档案馆) - 台北榮民總醫院 毒物科 楊振昌醫師
- ^ preamble to the IARC Monographs (页面存档备份,存于互联网档案馆)pdf
- ^ 存档副本. [2014-11-24]. (原始内容存档于2020-02-03).
- ^ 指定「危險物與有害物標示及通識規則 「危險物與有害物標示及通識規則」第二條第二款 」第二條第二款公告適用之 1,089 種危害物質名單 (PDF). [2014-11-24]. (原始内容存档 (PDF)于2014-11-29).
- ^ [1][永久失效連結]
- ^ Bracken Fern - Bracken Fern or Brake Fern (Pteridium aquilinum) - Plants toxic to animals (页面存档备份,存于互联网档案馆) - Veterinary Medicine library at U of Illinois
- ^ 存档副本. [2014-11-24]. (原始内容存档于2019-07-28).
- ^ 存档副本 (PDF). [2014-11-24]. (原始内容存档 (PDF)于2016-03-03).
- ^ 存档副本. [2014-09-20]. (原始内容存档于2020-02-03).
- ^ 物質安全資料表 (页面存档备份,存于互联网档案馆) - 勞動部勞動及職業安全衛生研究所
- ^ 存档副本. [2014-11-24]. (原始内容存档于2014-11-18).
- ^ Press release No 208, 31 May 2011 (页面存档备份,存于互联网档案馆), IARC classifies Radiofrequency Electromagnetic Fields as possibly carcinogenic to humans
- ^ 二異氰酸甲苯 (页面存档备份,存于互联网档案馆) - 行政院毒災防救管理資訊系統
- ^ 2,4-二異氰酸甲苯健康危害 (页面存档备份,存于互联网档案馆) - 國立陽明大學環境衛生研究所
- ^ 中華民國七十六年一月十五日,台北縣某工廠因二異氰酸甲苯(Toluene diisocyanate , TDI) (页面存档备份,存于互联网档案馆) - 衛生福利部疾病管制署
- ^ 世卫组织:阿斯巴甜可能致癌. 联合国新闻. 2023-07-13 [2023-07-14] (中文).
- ^ J, Wilbourn; C, Partensky; WG., Morgan. Printing Processes and Printing Inks, Carbon Black and Some Nitro Compounds. International Agency for Research on Cancer. 1996 [2023-10-31]. PMID 9148039. (原始内容存档于2022-12-22).
- ^ Printing Processes and Printing Inks, Carbon Black and Some Nitro Compounds. IARC Publications Website. [2023-10-31]. (原始内容存档于2023-10-31).
外部链接
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