促甲状腺激素释放激素受体

Thyrotropin-releasing hormone receptor
促甲状腺激素释放激素受体
Thyrotropin-releasing hormone receptor; 促甲状腺激素释放激素受体
标识
代号	TRHR; TRH-R
扩展标识	遗传学：188545 鼠基因：98824 同源基因：20707 IUPHAR: TRH1 ChEMBL: 1810 GeneCards: TRHR Gene
基因本体论描述
分子功能	· thyrotropin-releasing hormone receptor activity;
细胞成分	· plasma membrane; · integral to plasma membrane;
生物过程	· G-protein coupled receptor signaling pathway;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体
物种	人类
Entrez	7201
Ensembl	ENSG00000174417
UniProt	P34981
mRNA序列	NM_003301
蛋白序列	NP_003292
基因位置	Chr 8:; 110.1 – 110.13 Mb
PubMed查询	[1]
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促甲状腺激素释放激素受体（英語：thyrotropin-releasing hormone receptor，TRHR）是一种与三肽促甲状腺激素释放激素结合的G蛋白偶联受体^[1]^[2]。TRHR表达于脑细胞中，在与TRH结合时会激活磷脂酶C增加细胞内的肌醇三磷酸含量。

参考文献

^ Yamada M, Monden T, Konaka S, Mori M. Assignment of human thyrotropin-releasing hormone (TRH) receptor gene to chromosome 8. Somat. Cell Mol. Genet. 1993, 19 (6): 577–80. PMID 8128317. doi:10.1007/BF01233384.
^ Gershengorn MC. Thyrotropin-releasing hormone receptor: cloning and regulation of its expression. Recent Prog. Horm. Res. 1993, 48: 341–63. PMID 8382829.

延伸阅读

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